:: Invited LecturesInnovation at Interfaces
Charles Cooney
Department of Chemical Engineering, Massachusetts
Institute of Technology, USA
The important problems and challenges in biochemical
engineering occur at disciplinary interfaces. Innovative
solutions to these problems require crossing multiple
disciplinary boundaries at the interfaces of biology,
chemistry and physics.
Lessons learned from innovation at interfaces will be
drawn using diverse examples in biochemical engineering.
Developing processes to convert lignocellulosic biomass into
new fuels and chemicals requires facing the physical reality
of converting a complex feedstock via novel biocatalytic
routes to products that are difficult to recovery from
dilute aqueous solution. Efficient optimization of cell
culture processes for biotherapeutics production can be done
through the use of microreactors in large scale experimental
design, but one must address the uncertainty of scale up
through an understanding of the physics of reactor design
and the influence on biological response. Design of solid
dosage forms of pharmaceutical products and processes for
their manufacture requires an understanding of both the
chemistry and physics of particulate materials and
multiscale analysis to translate this understanding into
process knowledge.
|
 Charles
L. Cooney is Professor of Chemical and Biochemical
Engineering, in the Department of Chemical Engineering. He
is the Faculty Director of the Deshpande Center for
Technological Innovation, Co-Director of the Program on the
Pharmaceutical Industry (POPI) and MIT faculty director of
the Consortium on Advanced Manufacturing for Pharmaceuticals
(CAMP). He obtained his Bachelor's degree in Chemical
Engineering from the University of Pennsylvania in 1966. His
Master's and Ph.D. degrees in Biochemical Engineering are
from MIT in 1967, and 1970, respectively. After a short
post-doctoral time at the Squibb Institute for Medical
Research in 1970, he joined the MIT faculty as an Assistant
Professor in 1970 and became a full Professor in 1982. He
received the 1989 Gold Medal of the Institute of
Biotechnological Studies (London), the Food, Pharmaceutical
and Bioengineering Award from the American Institute of
Chemical Engineers and the James Van Lanen Distinguished
Service Award from the American Chemical Society's Division
of Microbial and Biochemical Technology and was elected to
the American Institute of Medical and Biochemical Engineers.
He serves as a consultant to a number of biotech and
pharmaceutical companies, is on several editorial boards of
professional journals, sits on the Boards of Directors of
Genzyme, BioProcessors and Biocon, Ltd (India), and was a
member of the BP Technical Advisory Council from 2001-2007.
He chaired the FDA Advisory Committee for Pharmaceutical
Science from 2004-2006.
Prof. Cooney's research interests span a range of topics
in biochemical engineering and pharmaceutical manufacturing.
He has published over 300 research papers, over 30 patents
and co-authored or edited 5 books including the recently
published Development of Sustainable Bioprocesses: Modeling
and Assessment, Wiley Press 2006. He research interest
include manufacturing strategy in the pharmaceutical,
biotech and biofuels industries, as well as bioprocess
design, operation and control, and processing of
pharmaceutical powders. As founding faculty director of the
Deshpande Center he is interested in the process of
stimulating technological innovation and translating
innovation into new company creation.
In addition to his professional interests, Prof. Cooney
is a Trustee of Boston Ballet, and an Overseer of the Boston
Symphony Orchestra. Other interests include rock climbing,
skiing, high altitude mountaineering (with assents of
Denali, Ama Dablam, Mont Blanc, Kilimanjaro, Huascaran),
scuba diving and antique map collecting.
More:
http://web.mit.edu/CHEME/people/faculty/cooney.html |
