Elective Module E1: Nanobiotechnology

Note: Draft version

Coordination: João Pedro Conde/IST

The objective of this course is that the students understand in both breadth and depth the scientific and technological basis of Nanotechnology. Application areas include: micro and nanofabrications, MEMS and NEMS, micro reactors, lab-on-a-chip systems, micro total analysis systems, carbon nanotubes, nanowires, atomic force microscopy, atomic and molecular manipulation, molecular motors, biological factories, nanoparticles, nano biosensors, biochips and molecular electronics.

Topics  

Introduction

1. Introduction to BioMEMS, Nanotechnology and Bionanotechnology

Top-down

2. Silicon microfabrication including micromachining
3. Soft fabrication techniques
4. Microfluidic principles
5. Sensor principles and microsensors
6. Microactuators and drug delivery
7. Lab-on-a-chip/microreactor systems
8. Scanning probe microscopies – principles and applications

Bottom-up

9. Self-assembly and self-organization
10. Carbon-based nanostructures
11. Nanowires and quantum dots
12. DNA-based nanostructures
13. Genomics and DNA microarrays
14. Protein-based nanostructures
15. Proteomics and protein microarrays
16. Cell-chips
17. Emerging BioMEMS technology

 References:

• Nanobiotechnology: Concepts, Application and Perspectives, Edited by C.M. Niemeyer, C.A. Mirkin, Wiley-VCH, Weinheim, 2004.
• Introduction to Nanoscale Science and Technology, Edited by M. di Ventra, S. Evoy, J.R. Heflin, Jr, Springer, New York, 2004.
• Fundamentals of BioMEMS and Medical Microdevices, S.S. Saliterman, Wiley-Interscience, Bellingham, 2006.